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Journal of Occupational & Environmental Medicine

Ovid Technologies (Wolters Kluwer Health)

Preprints posted in the last 90 days, ranked by how well they match Journal of Occupational & Environmental Medicine's content profile, based on 17 papers previously published here. The average preprint has a 0.01% match score for this journal, so anything above that is already an above-average fit.

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Work-related Musculoskeletal Pain Among Factory Workers in Kigali: Prevalence and Coping Strategies

Dusabeyezu, P.; Sagahutu, J. B.; Kemigisha, J.

2026-08-25 occupational and environmental health 10.64898/2026.08.22.26361118 medRxiv
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Background: Work-related musculoskeletal pain (MSP) is a prevalent concern among factory workers, impacting productivity, absenteeism, and overall quality of life. Factory workers, who perform repetitive tasks and engage in physically demanding work, are particularly susceptible to work-related MSP. Methods: This descriptive cross-sectional quantitative study included 148 factory workers (29 females and 119 males) from two factories in Kigali, surveyed between November 2023 and January 2024. Data were collected using a structured questionnaire that included demographic items, the Modified Nordic Musculoskeletal Questionnaire (M-NMQ) to assess work-related musculoskeletal pain (MSP) symptoms in nine body regions over the previous 12 months and seven days, and questions regarding interference of symptoms with normal work activities. The Coping Strategies Questionnaire (CSQ) was administered to identify coping practices among factory workers. Data analysis comprised descriptive statistics, including mean, frequency, Wilson 95% confidence intervals, and percentage values, calculated using SPSS version 25.0. Results: Participants were predominantly male (119/148, 80.4%), and 98/148 (66.2%) had worked at the factory for more than five years. Overall, 113/148 reported symptoms in at least one body region during the previous 12 months (76.4%, 95% CI 68.9-82.5). The lower back (90/148, 60.8%), shoulders (71/148, 48.0%), neck (61/148, 41.2%), and knees (58/148, 39.2%) were most frequently affected. Symptoms prevented normal work for 41/148 (27.7%, 95% CI 21.1-35.4), and 57/148 reported symptoms during the previous seven days (38.5%, 95% CI 31.1-46.5). Among 113 participants with 12-month symptoms, the most frequent Always responses were seeking medical help (78/113, 69.0%), rest and recovery (75/113, 66.4%), and medication use (59/113, 52.2%); ergonomic adjustment was least frequent (10/113, 8.8%). Conclusion: Self-reported work-related MSP symptoms were common, particularly in the lower back and shoulder, while ergonomic adjustments were uncommon. Frequent medication use highlights the need for comprehensive interventions combining ergonomic training, physiotherapy, and adequate recovery; however, these findings do not establish causation or intervention effectiveness.

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Protecting the protectors: Occupational burden and management of work-related musculoskeletal disorders among Cameroonian healthcare professionals and the Sustainable Development Goals

Kum, M. B.; Meh, B. K.; Buh, F. C.; Mandengue, S. H.; Bopda, O. S. M.

2026-08-02 occupational and environmental health 10.64898/2026.07.30.26359338 medRxiv
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Work-related musculoskeletal disorders (WRMSDs) constitute the primary occupational health burden among healthcare professionals (HCPs) globally and directly threaten health workforce sustainability, a critical concern for Sustainable Development Goal 3 (Good Health and Well-being) and SDG 8 (Decent Work and Economic Growth). Despite high prevalence in Cameroon, downstream occupational effects and management strategies across hospital levels remain undocumented. A hospital-based, analytical cross-sectional study was conducted across five referral hospitals in Douala, Cameroon (2019-2022). A total of 561 HCPs were enrolled by stratified random sampling. The Modified Nordic Musculoskeletal Questionnaire and structured interviews assessed WRMSD occupational effects and management strategies. Data were analysed using IBM SPSS v26; chi-square tests and logistic regression assessed associations (p < 0.05). The 12-month WRMSD prevalence was 83.4% (468/561). WRMSDs caused absenteeism in 83.4% of affected HCPs ({chi}2 = 14.414; p < 0.001), reduced daily activity capacity in 55.6%, and job dissatisfaction in 60.4%; 38.9% were considering a career change. Management was predominantly reactive: fitness training (76.3%), rest (41.4%), and non-steroidal anti-inflammatory drugs (NSAIDs; 37.3%). Only 15.0% received physiotherapy referral, and no hospital had a formal WRMSD protocol. WRMSDs impose a substantial and measurable occupational burden on HCPs in Douala. Current management is reactive, non-standardised, and under-integrated with physiotherapy. Evidence-based, multicomponent prevention programmes, physiotherapy integration, and a national occupational health policy are urgently required to protect the healthcare workforce and advance SDG 3 and SDG 8 targets in Cameroon.

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Sociodemographic and occupational factors associated with general sick leave among public school teachers in Bogota: A retrospective cohort study, 2010-2025

Bayona-Rodriguez, H.; Sanchez-Santiesteban, D.; Buitrago, G.

2026-08-10 occupational and environmental health 10.64898/2026.08.06.26359845 medRxiv
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Background: General illness-related sick leave among teachers represents a relevant public health and workforce management issue. However, long-term population-based evidence describing its distribution and associated factors in Latin American urban educational systems remains limited. This study aimed to characterize the occurrence, distribution, duration, and sociodemographic, occupational, temporal, and territorial factors associated with general illness-related sick leave among public school teachers in Bogota between 2010 and 2025. Methods: A retrospective cohort study was conducted using integrated administrative databases from the Bogota District Department of Education. The primary outcome was the occurrence of at least one general illness-related sick leave episode in a teacher-month observation. Descriptive analyses were performed to characterize sociodemographic and occupational patterns. A multivariable logistic regression model was used to estimate associations. Month and year were included as temporal fixed effects to account for seasonal patterns, academic-calendar effects, pandemic-related disruption, and secular changes. Results: The cohort included 59,697 unique teachers, contributing 537,025 teacher-year observations from teachers with an active employment record between January 1, 2010, and July 31, 2025. Overall, 41.59% of teacher-year observations included at least one general illness-related sick leave episode, and 83.26% of teachers had at least one episode at any time during follow-up. Respiratory diseases accounted for the largest share of episodes, followed by musculoskeletal and infectious diseases. Mean duration varied substantially by diagnostic category, ranging from short respiratory and infectious episodes to longer absences related to neoplasms, circulatory diseases, injuries, and mental health conditions. In the multivariable teacher-month model, sick leave occurrence was associated with age, sex, occupational role, teaching area, contract type, locality, calendar month, and calendar year. Lower odds were observed among male teachers, principals, and teachers with provisional contracts, while temporal and territorial variation was observed across months, years, and localities. Conclusions: General illness-related sick leave among public school teachers in Bogota showed consistent sociodemographic, occupational, temporal, and territorial patterns. Respiratory and musculoskeletal conditions accounted for the largest share of episodes, while chronic, neoplastic, injury-related, circulatory, and mental health conditions were associated with longer durations. These findings provide population-level evidence to inform occupational health surveillance, seasonal preparedness, and workforce planning strategies within urban educational systems.

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Assessing hospital workers' health: a tool for longitudinal health monitoring in a public tertiary hospital in Brazil's Unified Health System (SUS)

Amancio, R. T.; Cruz, L. N.; Dantas, R. d. S.; Gomes, M. P.; Silva, A. d. A. B. d.; Brasil, P. E.

2026-08-31 occupational and environmental health 10.64898/2026.08.27.26361318 medRxiv
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Background: Health and administrative professionals in tertiary hospitals face high levels of occupational stress, mental illness, and multimorbidity. The integrated measurement of these multidimensional health aspects is essential for informing effective workplace health promotion strategies. Objective: To describe the general health status of federal public hospital staff and correlate the measured health dimensions to inform institutional health promotion initiatives. Methods: A cross-sectional, online survey study was conducted at Hospital Universitario dos Servidores do Estado (HUSE) between November and December 2025. Data collection was performed via online REDCap questionnaires covering sociodemographic profiles and validated instruments (SRQ-20, MIDAS, AUDIT, WHOQOL-BREF, PHI, WHOQOL-SRPB BREF, CBI, GPAQ, and EPSO). Descriptive statistics, comparisons across employment ties (permanent vs. contracted staff), and Spearman correlation matrices were calculated. Results: Among 197 accesses, 117 completed the informed consent, and 86 finished all questionnaires. Participants were predominantly female, aged 40 to 60 years, and Christian. Screening positivity was 25% for common mental disorders, 21% for headache-related disability, and 10% for harmful drinking. Burnout scores clustered in the second quartile, while quality of life, happiness, and spirituality scores were in the upper third. Median physical activity was 670 min/week. Mental symptoms (SRQ-20), headache (MIDAS), and burnout (CBI) correlated positively with each other and negatively with quality of life, happiness, spirituality, and institutional support (EPSO). Conclusion: The set of instruments proved feasible for situational health diagnosis among hospital staff. Although the sample size was limited in this baseline wave, the initiative fostered workplace health awareness, driving concrete initiatives, including an on-site functional gym and workplace vaccination campaigns.

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Strategies to Reach Employees Nurturing Guidance and Trust in Healthcare (STRENGTH): Understanding Employee Drivers for Employer-Based Influenza Vaccination Programs

Sanchez, A. P.; Isakari, K.; Keefe, M.; Isakari, M.; Sitapati, A.

2026-07-16 occupational and environmental health 10.64898/2026.07.13.26357995 medRxiv
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Background: Vaccine hesitancy and logistical barriers continue to limit influenza vaccination uptake among healthcare personnel. The STRENGTH initiative evaluated employee drivers of influenza vaccine acceptance in healthcare workgroups with lower vaccination compliance. Methods: This mixed-methods program evaluation used a custom Epic electronic medical record dashboard to identify workgroups with lower influenza vaccination rates, followed by focus groups, targeted worksite vaccination clinics, and an anonymous survey. Survey data from 73 respondents were analyzed using descriptive statistics, Mann-Whitney U tests, Kruskal-Wallis tests, chi-square or Fisher exact tests, and Spearman rank correlations. Results: Respondents had a mean age of 44.8 years (SD 11.3); 36 of 70 respondents reporting binary gender were male. Convenience of worksite vaccination received the highest importance ratings (mean 4.72/5), followed by protection from influenza (mean 4.38/5). Both were rated significantly above the neutral midpoint of 3 (Wilcoxon p<0.001). The strongest observed Spearman correlations were between peer pressure and leadership participation (rho=0.47) and between protection from influenza and willingness to receive a future combined influenza/COVID-19 vaccine (rho=0.42). Conclusions: Convenience and perceived protection were the most important vaccination drivers. Employer-sponsored workplace vaccination programs can reduce logistical barriers while providing opportunities for targeted education and trust-building. Keywords: influenza vaccination; healthcare workers; vaccine hesitancy; occupational health; workplace vaccination; employer-sponsored vaccination

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The Japanese version of the Musculoskeletal Pain Intensity and Interference Questionnaire for Musicians (MPIIQM-J): Translation, cultural adaptation, and validation in Higher Music Education Institutions

AKAIKE, M.; TANAKA, T.; SUZUKAMO, Y.

2026-08-21 occupational and environmental health 10.64898/2026.08.18.26360635 medRxiv
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Background Playing-related musculoskeletal disorders are highly prevalent among musicians, yet no validated The aim of this study was to translate and culturally adapt the MPIIQM into Japanese and to examine its psychometric properties in students of higher music education institutions (HMEIs). Methods Forward-backward translation followed ISPOR guidelines, with linguistic validation through pilot testing. Psychometric evaluation was conducted in instrumental music majors enrolled at nine HMEIs in Japan, combining in-person and online surveys. Exploratory factor analysis, Cronbach's , and Pearson correlations with the Brief Pain Inventory (BPI), QuickDASH, and QuickDASH Performing Arts Module (PAM) were computed in symptomatic respondents (n = 48). Symptom prevalence in the full HMEIs sample (n = 226) was compared with national data (Ministry of Health, Labour and Welfare in Japan, 2022) using binomial tests with Holm correction. Results Exploratory factor analysis yielded a two-factor structure (pain intensity; pain interference) explaining 76.8% of the variance. Cronbach's was .864 (pain intensity), .890 (pain interference), and .903 (total). The pain intensity subscale correlated strongly with BPI pain severity (r = .71), and the pain interference subscale correlated with the QuickDASH PAM (r = .62). Test-retest reliability could not be computed because only 9 of 30 retest respondents met inclusion criteria. HMEIs students reported significantly higher prevalence than national peers in 25 of 41 symptoms, most markedly stiff shoulders and low back pain. Conclusions The MPIIQM-J demonstrated adequate structural validity, internal consistency, and convergent validity, and is expected to be useful in educational and clinical settings.

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Biomechanical Analysis of Dynamic Gripping in Manual Laborers Exhibiting Work-Related Scapholunate Instability Signs

Bari, M. H.; Khalid, Z.; Ilyas, M.; Qaiser, S.

2026-06-30 occupational and environmental health 10.64898/2026.06.27.26356743 medRxiv
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ABSTRACT Background: Scapholunate instability (SLI) represents the most prevalent form of carpal instability and is increasingly recognized as a clinically significant occupational condition in manual-labor populations. Repetitive forceful gripping, sustained wrist loading, and awkward joint postures inherent to construction, manufacturing, and heavy industry may predispose workers to progressive scapholunate ligament compromise; however, the specific biomechanical mechanisms underlying dynamic grip force transmission in symptomatic laborers remain poorly characterized. Objective: This study aimed to quantify dynamic grip force profiles and wrist kinematics in manual laborers exhibiting clinical signs of scapholunate instability; compare these biomechanical parameters with asymptomatic worker controls; and identify occupation-specific loading patterns that may contribute to scapholunate ligament compromise. Methods: A cross-sectional observational design was employed. Forty-two male manual laborers, mean age 36.4 (SD 7.2 )years; mean occupational exposure 9.8 (SD 4.1) years, were recruited from construction and surgical instrument manufacturing sites in Sialkot District, Pakistan. Participants were stratified into a symptomatic group (n = 21) based on positive Watson scaphoid shift test, dorsal wrist pain, and functional limitation, and an asymptomatic control group (n = 21). Dynamic grip force was measured using a calibrated Jamar dynamometer across five standardized trials. Wrist kinematics were captured during a simulated gripping task using electrogoniometry. Surface electromyography (sEMG) recorded flexor digitorum superficialis, flexor carpi ulnaris, and extensor carpi radialis longus activity. Scapholunate gap was confirmed radiographically. Statistical analyses included independent samples t-tests, Pearson correlation, and logistic regression ( = 0.05). Results: Symptomatic workers demonstrated significantly reduced grip force (28.4 (SD 5.6) kg versus 41.7 (SD 6.3) kg; p < 0.001) and elevated wrist ulnar deviation during peak gripping (22.3 (SD 4.1) degrees versus 14.6 degrees (SD 3.8) degrees ; p = 0.002) compared with controls. sEMG amplitude of flexor digitorum superficialis was paradoxically elevated in the symptomatic group (mean difference 18.3 microvolts; 95% CI 11.4-25.2), suggesting compensatory hyperactivation. Scapholunate gap correlated positively with years of occupational exposure (r = 0.67; p < 0.001). Logistic regression identified wrist ulnar deviation angle (OR = 2.14; 95% CI 1.43-3.19) and grip force asymmetry (OR = 1.87; 95% CI 1.21-2.89) as independent predictors of instability signs. Conclusions: Manual laborers with work-related scapholunate instability signs exhibit distinct biomechanical signatures during dynamic gripping, including reduced force output, abnormal wrist posture, and compensatory neuromuscular recruitment. Occupational exposure duration is a significant predictor of radiographic scapholunate dissociation. These findings support the integration of ergonomic risk screening and early biomechanical assessment into occupational health protocols for manual labor populations in low- and middle-income settings. Abbreviations: CI: confidence interval, DRUJ: distal radioulnar joint, EMG/sEMG: (surface) electromyography, FCU: flexor carpi ulnaris, FDS: flexor digitorum superficialis, MSD: musculoskeletal disorder, OR: odds ratio, ROM: range of motion, SL/SLI: scapholunate/scapholunate instability, SLIL: scapholunate interosseous ligament, SLAC: scapholunate advanced collapse, WMSDs: work-related musculoskeletal disorders, SD: standard deviation. Keywords: scapholunate instability; dynamic gripping; manual labor; wrist biomechanics; carpal kinematics; occupational ergonomics; grip force; electromyography; Watson scaphoid shift test; work-related musculoskeletal disorders

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Chronotype distinctness a key risk factor for emotional and cognitive disruption in shift working nurses

Davies, A.; Hickman, R.; Cai, Z.; Lai, D. J.; Hampshire, A.; Hellyer, P. J.; Shergill, S.; D'Oliveira, T.

2026-08-24 occupational and environmental health 10.64898/2026.08.21.26361010 medRxiv
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The prevalence of shift work-centric industries and the rise of flexible working render it crucial to investigate the health risks posed by unnatural patterns of work and sleep. Shift working in healthcare has been linked to emotional dysregulation, reduced alertness, and cognitive impacts, with Shift Work Disorder (SWD) classified as a circadian rhythm sleep-wake disorder in the DSM-5. These impacts have historically been attributed to schedule-related sleep disturbances; however certain individuals appear more acutely affected. One measure of individual inflexibility to altered routines is chronotype distinctness, an amplitude dimension of the Caen Chronotype Questionnaire (CCQ). Here, we use Structural Equation Modelling (SEM) to unravel the mechanisms by which sleep and chronotype distinctness govern the neuropsychiatric symptom profiles of a cohort of National Health Service (NHS) shift workers (n=102). We constructed a measurement model, extracting latent constructs from questionnaires for sleep disturbances (PSQI), chronotype distinctness (CCQ), mood disorder (MDQ), depression (PHQ8) and emotional reactivity (ERS), and cognitive assessments. Correlations were identified between constructs, then translated into two SEMs - day and rotating shifts respectively - with sleep and distinctness as predictors of detrimental effects. Models were tested for direct effects, significant paths, and overall model fit. We found that, whilst sleep governed fatigue-based symptoms in day-shift workers, chronotype distinctness determined the severity of adverse effects in rotating-shift workers, including mood disorders and cognitive impairments. We surmise that high chronotype distinctness should be considered a risk factor for adverse effects surrounding night and rotating-shift work, and that interventions should incorporate chronotype-specific remediation.

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Differences in domain-specific composition of 24-hour physical behaviors across occupational groups

Hirvonen, N.-P.; Niemela, M.; Leinonen, A.-M.; Farrahi, V.

2026-07-27 epidemiology 10.64898/2026.07.23.26358754 medRxiv
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Purpose: Physical behaviors, including physical activity, sedentary time, and sleep, are associated with health and together comprise the 24-hour day. Among working-aged adults, the composition of these 24-hour physical behaviors may vary across occupations, but the extent of these differences remains unknown. This population-based study examined how the composition of 24-hour physical behaviors differs in working-aged adults across occupational groups during work and leisure time. Methods: The study population consisted of 2,809 adults from the Northern Finland Birth Cohort 1966 46-year follow-up study, who wore a hip-worn accelerometer for 14 days. The accelerometry data was combined with self-reported diaries to determine time in bed and work hours. Four occupational groups were aggregated based on occupation type and occupational skill level: high-skill white-collar, low-skill white-collar, high-skill blue-collar and low-skill blue-collar. Time spent on physical behaviors during workdays (including working hours and leisure time separately) and non-workdays were calculated. Differences in physical behavior compositions were assessed using a compositional data analysis approach based on log-ratios of geometric means, with the low-skill blue-collar group as the reference group. Results: Significant differences in 24-hour physical behaviors across occupational groups were mainly observed during workdays. During workday working hours, all other occupational groups had less physical activity (both moderate-to-vigorous and light-intensity physical activity) compared to the reference group. During workday leisure time, significant differences were observed in all physical behaviors, except for sedentary time. On non-working days, the high-skill white collar group had higher moderate-to-vigorous physical activity compared to the reference group. Conclusions: The composition of domain-specific 24-hour physical behaviors differs across occupational groups, particularly during workdays.

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Active commuting, anxiety symptoms and mental wellbeing: a dose-response study

Joensuu, L.; Jussila, J. J.; Lanki, T.; Tiittanen, P.; Pasanen, T. P.; Ekelund, U.; Halonen, J. I.

2026-06-15 public and global health 10.64898/2026.06.12.26355515 medRxiv
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Climate change draws attention to the planetary health perspective in sport and exercise sciences, that is, to physical activity that supports both human wellbeing and environmental sustainability. Active commuting is a sustainable form of physical activity with well-established somatic health benefits. However, more knowledge is needed on its relationship with mental health. We examined dose-response associations between active commuting, anxiety symptoms, and mental wellbeing among Finnish adults, and whether green commuting environment moderates these relationships. We used data from the cross-sectional Environment and Health Survey collected in June-September 2023 in the ten largest cities in Finland. Employed participants with data on anxiety symptoms (Generalized Anxiety Disorder-7, GAD-7), mental wellbeing (World Health Organization-Five Well-Being Index, WHO-5), commuting profile over a year (mode, frequency, distance, and perceived greenness along the commute route), and sociodemographic and lifestyle factors were included (n=1,672; mean age 45.3 years; 53.8% women). Active commuting was defined as travelling the entire commute by walking or cycling (including e-biking) that was converted into approximated annual km/week and MET-h/week. We used linear and logistic regression with restricted cubic splines to evaluate dose-response associations, adjusted for key covariates. The role of perceived greenness was tested using an active commuting x commute greenness interaction term. We found no dose-response relationships between active commuting and anxiety symptoms or mental wellbeing in any of the models. No effect modification by commute greenness was observed. More research on how active commuting may support planetary health from a mental health perspective is needed.

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Occupational Physical Activity Paradox and Incident Cardiovascular Disease: Does Exposure Classification Matter?

Okoro, W. O.; Demou, E.; Celis-Morales, C. A.; Ryde, G. C.

2026-07-27 occupational and environmental health 10.64898/2026.07.23.26358767 medRxiv
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Objectives The association between occupational physical activity (OPA) and cardiovascular disease (CVD) may depend on how OPA is classified. This study examined the association between OPA and incident CVD using individual level and occupational group level classifications, and assessed whether factors contributing to attenuation differed. Methods A total of 137,592 employed UK Biobank participants aged 40 to 69 years who were free of CVD at baseline were included. OPA was classified using (i) individual level self reported physical activity at work and (ii) occupational group level two digit Standard Occupational Classification. Associations with incident CVD were examined using Cox proportional hazards models. Attenuation of associations by sociodemographic, lifestyle, health, occupational and psychosocial factors was assessed using univariate adjustments and Heller's coefficient. Results During 1,656,378 person-years of follow up (median 12.6 years), 10,465 incident CVD events occurred. The association between OPA and CVD differed markedly according to exposure classification. High individual level self reported OPA was associated with increased CVD incidence after full adjustment [hazard ratio (HR) 1.19, 95% confidence interval (CI) 1.10 to 1.27]. In contrast, no association was observed when OPA was classified at the occupational-group level using Standard Occupational Classification groupings (HR 1.00, 95% CI 0.94 to 1.06). Sociodemographic and health factors accounted for the greatest attenuation across both classifications, whereas psychosocial factors contributed primarily to associations based on individual-level self-reported OPA. Conclusions The association between occupational physical activity and incident cardiovascular disease differed substantially according to how OPA was classified. These findings highlight exposure classification as a critical consideration when interpreting evidence on the physical activity paradox.

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Knowledge, attitudes, and practices related to ocular safety among maintenance workers in a Ghanaian university: A cross-sectional study

Kwarteng, C.; Brew, F. M.; Owusu, E.

2026-09-03 occupational and environmental health 10.64898/2026.09.01.26361906 medRxiv
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Occupational ocular injuries are a preventable yet neglected public health problem, particularly in low- and middle-income countries. Maintenance workers are exposed to diverse ocular hazards daily, yet compliance with protective measures is consistently poor. A descriptive cross-sectional study was conducted among 85 maintenance workers at the Maintenance and Essential Services Organization (MESO) of Kwame Nkrumah University of Science and Technology (KNUST), Ghana, recruited through stratified convenience sampling across seven occupational sections. A structured questionnaire assessed knowledge of ocular hazards and protective equipment, attitudes toward ocular safety, and safety practices. Data were analyzed using IBM SPSS version 26 (IBM Corp., Armonk, NY, USA); chi-square and Fishers exact tests assessed associations (p < 0.05). Participants were predominantly male (84/85, 98.8%), with a mean age of 44.5 {+/-} 10.4 years. Overall knowledge was good (mean 9.40 {+/-} 1.59 out of 11), but attitude and practice scores were average (2.78 {+/-} 0.92 and 3.27 {+/-} 0.93, respectively). Most workers correctly identified goggles and face shields as protective, but only about half recognized that ordinary sunglasses and spectacles offer inadequate protection. Although 97.6% (83/85) recognized the need for ocular protection, only 7.1% (6/85) reported consistent protective eyewear use, and fewer than half (45.9%, 39/85) had received formal ocular safety training. Routine general protective equipment use was significantly associated with ocular protection use (Fishers exact test, p = 0.011). Sand and dust particles were the leading causes of injury and only 25% (5/20) of injured workers sought formal care. Workers demonstrated good knowledge but poor attitudes and practices toward ocular safety, suggesting that knowledge alone does not translate into protective behaviour even within a relatively well-resourced institutional setting. Findings suggest that limited access to task-appropriate protective eyewear may represent an important institutional barrier. Institutional PPE supply and section-specific safety training are essential to bridge this knowledge-practice gap.

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Using Social Determinants of Health ICD-10 Z-codes to Identify Non-Medical Factors among Asthma Hospitalizations in the United States, 2016-2022

Wang, N.; Huang, H.; Chu, J.; Hsu, J.

2026-08-22 public and global health 10.64898/2026.08.19.26360844 medRxiv
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Objectives: Healthcare data can reveal actionable opportunities to prevent asthma hospitalizations. Limited national-level data exist regarding social determinants of health (SDOH) and asthma hospitalizations. We examined SDOH-related International Classification of Diseases, Tenth Revision (ICD-10) Z-codes in national administrative data on asthma hospitalizations and described patient- and hospital-level characteristics associated with documented SDOH Z-codes. Methods: Pooled cross-sectional analysis of 2016-2022 Nationwide Inpatient Sample for 200,452 U.S. hospitalizations (all ages) with a primary diagnosis of asthma. Presence of SDOH Z-codes (codes Z55-Z65) assessed by descriptive statistics and multivariable logistic regression to calculate odds ratios (ORs) and 95% confidence intervals (95% CIs) for associations between SDOH Z-codes and patient- and hospital-level characteristics. Results: In unweighted analyses, 3,149 asthma hospitalizations had SDOH Z-codes (1.57%). The most common SDOH Z-codes were homelessness (Z59.0; n=942) and unemployment (Z56.0; n=349). Weighted chi-square analyses found all selected variables were associated with asthma hospitalization SDOH Z-code documentation. Logistic regression results varied; adjusted odds for SDOH Z-code documentation were higher for asthma hospitalizations involving male patients (aOR=1.51; 95% CI, 1.39-1.63; P < .001) compared to female patients. Asthma hospitalizations involving rural hospitals had lower odds of SDOH Z-codes documentation (aOR=0.57; 95% CI, 0.47-0.70; P < .001) compared to urban teaching hospitals. Conclusions: National 2016-2022 data indicate housing- and employment-related Z-codes were the most commonly documented SDOH within asthma hospitalizations. Future analyses could consider establishing causality and exploring how relationships between these SDOH may be used by public health practitioners and others to improve program interventions.

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Incidence of Fractures and Development of the Fracture Risk Model (FRM) in a Population-Based Cohort Study in Abu Dhabi

Alketbi, L. B.; AlKaabi, J.; Bin Hraiz, S.; AlNeyadi, H.; Alyahyaei, M.; AlAlawi, S.; Mohamed, Y.; Alkaabi, M.; Alwaqfi, Y.; Al Shukri, S.; Alshamsi, S.; Al Kalbani, S.; Hantash, A.; Saeed, E.; Alantali, W.; Elbeheiry, B.; Omara, A.; Al Khouri, A.; AlNuaimi, F. K.; Moussa, M.; Abdelbaki, H.; Nagelkerke, N.

2026-07-24 primary care research 10.64898/2026.07.23.26358200 medRxiv
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Abstract Fractures in older adults cause high morbidity and mortality. This study aims to identify fracture incidence and risk factors, and to develop the Fracture Risk Model-Abu Dhabi (FRM-AD). Method This retrospective cohort study of 1757 males and females aged 40+ from Abu Dhabi, United Arab Emirates, who participated in a screening program from 2016 to 2020, followed until 2024 for 4.7 years, SD =1.8. It utilized Electronic Medical Records (EMRs) data and telephone interviews. The outcome assessed was the occurrence of fractures. Results There were 58 out of the 1149 females (5.0%) and 26 out of the 608 males (4.3%) who had at least one incident fracture. Hip and vertebral fractures accounted for 12.1% and 11.5%, respectively. There was an annual incidence of 10.5 fractures per 1,000 person-years, 10.7 cases among females and 9.9 among males, rising after age 80 to 39.1 among females and 25.3 among males. Fracture Predictors identified using Poisson regression analysis were older age, smoking, history of previous fracture(s), interaction of history of fracture in a parent with a family history of osteoporosis, positive history of hip fracture in a parent after the age of 40, lack of dyslipidemia diagnosis and the interaction of diabetes mellitus diagnosis and family history of osteoporosis. A higher Body Mass Index (BMI) increased the risk of fractures in this cohort, especially in obese males. Logistic regression of variables at the end of follow-up showed that lower latest vitamin D levels were associated with increased fracture risk. FRM-AD, derived using Poisson regression, performed well in predicting fractures, with Receiver Operating Characteristic (ROC) curves of 0.736 (0.677-0.794) and 0.742 (0.684-0.800) without and with BMD, respectively. The FRAX AUC to predict MOF and hip fracture ranged between 0.624 and 0.683. Conclusion In this Emirati cohort, the locally derived FRM-AD showed moderate discrimination for incident fracture and outperformed FRAX-AD, suggesting that a locally derived model may improve fracture risk stratification. Several risk factors and predictors were identified that can be targeted for prevention.

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On-site AASM-accredited sleep facility status and hospitalization outcomes among adults admitted with acute hypercapnic respiratory failure: a retrospective cohort study

Flores, A.; Bin Jamil, S.; Gudleski, G.; Monegro, A.

2026-07-30 respiratory medicine 10.64898/2026.07.28.26359158 medRxiv
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Objectives: Acute hypercapnic respiratory failure (AHRF) is a common cause of hospitalization among adults with chronic respiratory and sleep-related disorders. We evaluated whether admission to hospitals with an on-site American Academy of Sleep Medicine (AASM)-accredited sleep facility was associated with length of stay (LOS) and hospitalization cost among adults admitted with AHRF. Methods: We conducted a retrospective cohort study using the Healthcare Cost and Utilization Project New York State Inpatient Database from 2017 to 2021. Adults admitted to hospitals outside New York City were included because hospital density, referral patterns, and access to specialty services differ from those in New York City. Hospitals were classified by the presence of an on-site AASM-accredited sleep facility, used as a structural proxy for institutional sleep medicine capacity. LOS and hospitalization cost were log10-transformed before analysis. We used bivariate analyses and hierarchical multivariable linear regression models adjusting for demographic, clinical, socioeconomic, and hospital-level covariates. Results: A total of 3,247 adults met inclusion criteria. In unadjusted analyses, admission to hospitals with an on-site AASM-accredited sleep facility was associated with shorter LOS and lower hospitalization cost. After adjustment, sleep facility status was not independently associated with either outcome and did not improve model fit. Greater comorbidity burden was the strongest independent predictor of both longer LOS and higher cost. Housing instability and race categorized as other than White were also associated with higher resource use. Chronic obstructive pulmonary disease was independently associated with shorter LOS and lower cost. Conclusions: Among adults hospitalized with AHRF, LOS and hospitalization cost were more strongly associated with comorbidity burden and socioeconomic disadvantage than with the presence of an on-site AASM-accredited sleep facility. These findings suggest that accreditation status alone may not capture inpatient sleep medicine processes most relevant to acute respiratory care.

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The Right to Sexual and Reproductive Health among Migrant Workers in Taiwan: Stakeholder Perspectives through an AAAQ Analysis

Tang, P.; Lu, M. W.-H.; Yeung, K.-T.; Guo, B. J.; Wei, K.-F. N.

2026-08-31 public and global health 10.64898/2026.08.26.26361458 medRxiv
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Background Global labor migration from LMIC to higher-income destinations has expanded rapidly, placing increasing pressure on destination-country health. Existing research on cross-border migrant workers has focused largely on occupational health, general healthcare utilization, and disease-specific risks, while there is considerably less evidence on their sexual and reproductive health. This study contributes to this understudied field by examining the policy and health-system factors that shape the sexual and reproductive health services for migrant workers in Taiwan. Methods A qualitative study was conducted in Taiwan between November 2025 and August 2026. 22 stakeholders were purposively recruited from academia, healthcare, nongovernmental organizations, government, labor brokerage, and employers. Data were collected through semi-structured interviews and small focus groups. Interviews were conducted in Mandarin Chinese, transcribed verbatim, and translated into English. Data were analyzed using framework analysis combining deductive coding based on the AAAQ framework with inductive coding of implementation and contextual themes. Results Gaps were identified across all four AAAQ dimensions. Participants described limited migrant-responsive SRH programming; physical, financial, administrative, social, and information barriers; shortcomings in linguistic and cultural responsiveness; and weaknesses in interpretation, coordination, and continuity of care, despite generally favorable views of Taiwan's clinical quality. Conclusions Our findings show that broad insurance coverage and strong clinical capacity do not by themselves ensure the realization of migrant workers' SRHR. In Taiwan, rights were mediated through labor brokerage, gendered live-in work arrangements, and fragmented governance across health, labor, immigration, and social-welfare systems. Improving migrant SRHR therefore requires stronger implementation of existing protections, reduced dependence on informal intermediaries, and more integrated institutional responsibility for cross-sector migrant health needs.

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Demographic and occupational differences in physical activity and walking pace in UK healthcare workers: a nationwide longitudinal cohort study

Owen, J.; Martin, C. A.; Edwardson, C.; Lamb, D.; Gray, L. J.; Hadjiconstantinou, M.; Oliver, E. J.; Goss, C.; Reilly, H.; Yates, T.; Woolf, K. A.; Pareek, M.

2026-06-29 public and global health 10.64898/2026.06.26.26356302 medRxiv
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Objectives: To examine how self-reported physical activity and walking pace in UK healthcare workers differ ethnicity, migration status, and job role. Design: Prospective cohort study with 6 waves of data collection between 2020 and 2025, analysed using multi-level logistic regression, informed by the UK REACH patient and professional advisory group. Setting: Healthcare settings across the UK. The United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers (UK-REACH) cohort. Participants: 18,721 healthcare workers employed in the UK: 28.2% Allied Health Professionals; 75% female; 34% from ethnic minority backgrounds; and 32% born overseas. Main outcome measures: Physical activity and walking pace, as measured by the General Practice Physical Activity Questionnaire (GPPAQ). A Total Physical Activity score, and a separate Exercise and Cycling score excluding occupational physical activity were derived. Results: Walking pace and physical activity varied significantly by ethnicity, migration status and job role. Compared to White UK-born staff, slower walking pace was reported in ethnic minority staff, with differences greater in staff born overseas (e.g. Asian UK (aOR 0.63, 95%CI 0.56 to 0.71, p<0.001), Asian overseas (aOR 0.38, 95%CI 0.35 to 0.42, p<0.001)). Compared to White UK-born staff, lower odds of reporting being physically active were reported in multiple ethnic groups. Differences were larger for Exercise and Cycling, indicating that occupational physical activity accounted for a large proportion of total physical activity in several groups (e.g. Total Physical Activity: Asian overseas-born (aOR 0.79, 95%CI 0.72 to 0.87, p<0.001); Exercise and Cycling: Asian overseas-born (aOR 0.61, 95%CI 0.56 to 0.67, p=<0.001). Compared toMedicalstaff, Nursing and Midwifery staff, Pharmacy staff, Dental staff, Other staff, and Healthcare Scientists hadsignificantly lower odds of reporting being physically active. Ambulance staff had higher odds of reporting being physically active when using the Total Physical Activity score (aOR 1.64, 95%CI 1.37 to 1.97 p<0.001), but lower odds for Exercise and Cycling (aOR 0.61 95%CI 0.53 to 0.72, p<0.001). Conclusions: Self-reported physical activity and walking pace vary significantly in UK healthcare workers, by ethnicity, migration status, and job role. Our findings have important implications for understanding workforce health and ethnic health inequalities.

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Associations between occupations and the occurrence of sarcomas: results of the French population-based case-control study ETIOSARC

GRAMOND, C.; Guillemin, L.; Coureau, G.; Systchenko, T.; Hammas, K.; GASH Illescas, A.; Delafosse, P.; Blay, J.-Y.; Ducimetiere, F.; Penel, N.; Toulmonde, M.; Le Loarer, F.; de Pinieux, G.; Baldi, I.; Monnereau, A.; Lacourt, A.; Mathoulin-Pelissier, S.; Amadeo, B.

2026-07-22 epidemiology 10.64898/2026.07.20.26358458 medRxiv
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Objective Sarcomas are rare tumors of connective tissue that can develop in soft-tissue, viscera organs, or bones. Previous occupational studies have mainly focused on men and soft-tissue sarcomas. This study describes associations between occupations and sarcomas, in men and women, for soft-tissue sarcomas (STS), including visceral sarcomas, and bone sarcomas (BS). Methods The ETIOSARC study was a multicenter case-control study conducted across six French geographical areas between 2019 and 2023. Occupational histories were collected by interview and coded according to the International Standard Classification of Occupations (2008). Conditional logistic regression models were applied to estimate odds ratios with 90% confidence intervals for each occupation included in the study. Results A total of 374 male cases (336 STS and 38 BS), 371 female cases (335 STS and 36 BS), and 1,387 controls were included. Positive associations were observed among male STS for painters (OR=5.37, 90% CI=1.83-15.71), waiters (OR=4.54, 90% CI=1.88-10.97), and among male BS for electricians (OR=3.67, 90% CI=0.91-14.86). Among women, increased STS risk was found among real estate agents (OR=3.48, 90% CI=1.03-11.79), food preparation assistants (OR=3.47, 90% CI=1.09-11.04), and administrative and executive secretaries (OR=2.37, 90% CI=1.45-3.86). For BS, a higher risk was observed among sales workers (OR=5.61, 90% CI=1.65-18.99). Conclusions Our study highlights hitherto unreported occupational associations with sarcomas, among both men and women, as well as the importance of sex-stratified analyses. Further research should aim to confirm these results and disentangle the respective roles of occupational exposures, environmental factors, and lifestyle characteristics.

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The hidden productivity toll of perimenopause: symptom-driven work impairment during women's prime working years

Xu, Y.; Prentice, C.; Hewings-Martin, Y.; Cunningham, A. C.; Zhaunova, L.; Puig-Junoy, J.

2026-07-07 health economics 10.64898/2026.07.05.26357306 medRxiv
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Perimenopausal women, often in the prime of their careers, make up a significant proportion of the workforce. Previous studies have revealed the significant symptoms burden associated with perimenopause, yet its workplace and economic consequences remain poorly understood. We examined work impairment by symptom severity and across reproductive stages in a cross-sectional survey of U.S. women aged 35-59 (n=945), using the Work Productivity and Activity Impairment questionnaire and Menopause Rating Scale. We then estimated associated productivity losses using a human capital approach. Perimenopausal women were equally likely to remain in the labour force as premenopausal women (76.6% vs. 78.0%) but reported substantially higher work impairment (22.5% vs. 12.7%). Work impairment rose from 3.4% among women with minimal symptoms to 33.4% among those with severe symptoms and was driven predominantly by presenteeism rather than absenteeism. Somatic and psychological symptoms showed the strongest associations with work impairment, whereas urogenital symptoms were not significantly associated. The observed work impairment translated into an estimated annual productivity loss of approximately $6,061 per woman in perimenopause and a societal burden of $56.7 billion in the United States. These findings suggest that perimenopause is a substantial but under-recognised workplace health challenge, requiring better recognition and tailored, symptom-matched, workforce support. Keywords: perimenopause, symptom burden, work impairment, productivity loss.

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Performance management systems among physiotherapists in public rehabilitation centers in Bangladesh: A cross-sectional study of the health workforce

Kanan, S.; Halder, P.; Shuchorit, A.; Rahman, M. H.; Trikta, T. G.; Liza, T. I.; Borsha, B. R.; Kays, I.; Ahmed, R.

2026-07-13 public and global health 10.64898/2026.07.09.26357613 medRxiv
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Health workforce performance is central to service quality, yet little empirical work has examined how performance management systems operate for physiotherapists in rehabilitation services in low- and middle-income settings. This cross-sectional study assessed the current state, perceived effectiveness, and process gaps of performance management systems among physiotherapists working in public rehabilitation centers in Dhaka, Bangladesh. A pretested semi-structured questionnaire was administered to 105 physiotherapists between September and October 2025. Descriptive statistics were used to summarize participant characteristics and performance management indicators. Wilson 95% confidence intervals were estimated for key proportions. A nine-item exploratory performance management system maturity score was constructed from process indicators. Fisher exact tests with Cramer's V were used to examine associations with perceived system effectiveness, and exploratory logistic regression estimated odds ratios for effective or moderately effective performance management. The mean age of respondents was 31.6 years, 56 of 105 were male, and 85 of 105 had graduate or postgraduate qualifications. Formal performance management systems were reported by 102 of 105 respondents (97.1%, 95% CI 91.9-99.0). Standardized appraisal timing and method, assessment form use, performance planning, and formal evaluation systems were each reported by about 60-70% of participants. Reward-performance linkage was perceived as motivating by 97 of 105 respondents (92.4%, 95% CI 85.7-96.1). Overall, 81 of 105 respondents (77.1%, 95% CI 68.2-84.1) rated the system as effective or moderately effective. Training recipient category was associated with perceived effectiveness (Fisher exact p=0.0035; Cramer's V=0.363), as was perceived appropriateness of the process (p=0.0323; Cramer's V=0.258). The maturity score was not independently associated with perceived effectiveness in exploratory regression. Public rehabilitation centers in Dhaka appear to have formal performance management systems, but the systems are only moderately developed. Strengthening training coverage, transparent evaluation criteria, routine feedback, and formal system review may improve staff confidence in performance management processes.