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Journal of Occupational & Environmental Medicine

Ovid Technologies (Wolters Kluwer Health)

Preprints posted in the last 90 days, ranked by how well they match Journal of Occupational & Environmental Medicine's content profile, based on 17 papers previously published here. The average preprint has a 0.01% match score for this journal, so anything above that is already an above-average fit.

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Effectiveness of a 12-week multicomponent occupational lifestyle intervention to increase physical activity among Japanese teleworkers: a cluster randomised controlled trial (TELEWORK study)

Kim, J.; Nakata, Y.; Wada, A.; Kanamori, S.; Yoshimoto, T.; Tsukinoki, R.; Umishio, W.; Shiomitsu, T.; Yoshioka, N.; Yoshiba, K.; Gosho, M.; Kai, Y.

2026-03-26 occupational and environmental health 10.64898/2026.03.23.26349125 medRxiv
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BackgroundTeleworking is associated with lifestyle risk factors, such as insufficient physical activity (PA) and increased sedentary time (ST); however, effective interventions tailored to teleworkers are lacking. We aimed to evaluate the effectiveness of a 12-week multicomponent occupational lifestyle intervention on daily step counts among Japanese teleworkers. MethodsThis 12-week, two-arm, parallel-group, cluster randomised controlled trial conducted across 12 clusters in six Japanese companies involved 310 teleworkers (mean age 43.0 years; 72.6% men) randomized to the intervention (6 clusters, n=156) or a waitlist control group (6 clusters, n=154). The multicomponent occupational lifestyle intervention included individual (online lectures, feedback, and email messages), physical (posters and a pop-up), and organizational (encouraging messages from an executive) strategies. The primary outcome was the change in daily step counts, measured using an accelerometer over 14 consecutive days at baseline and at week 12. Analyses were based on the intention-to-treat approach using a generalised estimating equation model. FindingsThe intervention group showed an adjusted mean change in daily step counts of +219 steps (95% confidence interval [CI] -165 to 604), compared with +188 steps (95% CI -183 to 560) in the control group. The adjusted between-group difference was +55 steps (95% CI -550 to 660; p=0.844). No significant effects on the secondary outcomes (ST, light PA, or moderate-to-vigorous PA) were observed. InterpretationThe multicomponent occupational lifestyle intervention did not significantly increase daily step counts among Japanese teleworkers. Therefore, further studies should be done on tailored interventions for teleworkers. Research in contextO_ST_ABSEvidence before this studyC_ST_ABSTeleworking has increased globally, particularly following the coronavirus disease pandemic, and has been associated with reduced physical activity and increased sedentary behaviour, both of which are risk factors for cardiovascular disease. Previous studies have also reported that telework environments may contribute to musculoskeletal and other somatic symptoms. Multicomponent interventions in traditional office settings can effectively increase physical activity and reduce sedentary time. These interventions commonly employ strategies at multiple levels of the social-ecological model, including individual approaches (e.g., lectures or incentives), interpersonal approaches (e.g., team-based activities), environmental modifications (e.g., office rearrangements or sit-stand desks), and organisational support (e.g., leadership encouragement). The applicability of such interventions to teleworking populations remains unclear because teleworkers face distinct challenges such as social isolation, blurred work-life boundaries, and heterogeneous home working environments. These contextual differences highlight the need for interventions specifically tailored to teleworkers. Added value of this studyWe evaluated the effectiveness of a multicomponent occupational lifestyle intervention specifically designed for teleworkers, a population whose work environment differs substantially from traditional office settings. Our findings provide novel evidence that can inform the development of more targeted strategies to promote physical activity in evolving work environments. This study also provides objective measurements of physical activity using accelerometers, enabling detailed evaluation of step counts, sedentary time, and different activity intensities among teleworkers. Additionally, we used daily diaries to distinguish activity patterns across workdays, weekends, teleworking days, and commuting days, providing a nuanced understanding of behavioural patterns in remote work contexts. Implications of all the available evidenceOur findings indicate that low-cost, remotely delivered multicomponent interventions may be insufficient to produce meaningful behavioural change among teleworkers. Similar strategies, including individual, physical, and organisational components, have been effective in traditional workplace interventions; however, their implementation in teleworking environments may not adequately address the specific challenges faced by remote workers. In particular, the lack of strong sociocultural support mechanisms, such as team-based step competitions or workplace champions, may limit engagement and reduce the effectiveness of such programmes. Therefore, further investigation is needed to explore more diverse and targeted intervention strategies, identify the specific needs and behavioural patterns of teleworkers, and apply more precise eligibility criteria to better address heterogeneity within teleworking populations.

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Cohort profile: Description of the GIG-OSH longitudinal cohort on occupational safety and health of digital platforms workers in Europe

Belvis, F.; Vicente-Castellvi, E.; Verdaguer, S.; Gutierrez-Zamora, M.; Benach, J.; Bodin, T.; Gevaert, J.; Girardi, S.; Harris, J.; Ilsoe, A.; Kokkinen, L.; Larsen, T. P.; Lee, S.; Lundh, F.; Mangot-Sala, L.; Matilla-Santander, N.; Merecz-Kot, D.; Nurmi, H.; Warhurst, C.; Julia, M.

2026-03-06 occupational and environmental health 10.64898/2026.03.05.26347679 medRxiv
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PurposeThe GIG-OSH cohort was established to investigate the impact of digital platform work on occupational safety and health (OSH), working and employment conditions, and health in seven countries in Europe. ParticipantsThe cohort comprises 3,945 digital platform workers from seven European countries. The sample includes both web-based workers (e.g., micro-tasking, freelance design) and on-location workers (e.g., delivery, transport). Participants were recruited using non-probabilistic sampling strategies tailored to national contexts, including social media advertising, recruitment through micro-task platforms, and on-site field outreach. Multidimensional data have been collected through online surveys (implemented via REDCap) covering sociodemographic characteristics, working and employment conditions, psychosocial risks, algorithmic management, and physical and mental health indicators. Findings to dateParticipants had a mean age of 32.6 years at baseline (SD 10.4), and the majority are male (58.8%), with a higher concentration of migrants in on-location tasks (62.2%) compared to web-based tasks (48.8%). Regarding educational attainment, 55.4% of the total cohort holds a tertiary degree, reaching 64.4% among web-based workers. Platform work intensity varies significantly: on-location workers averaged 85.4 hours of work in the last month, while web-based workers averaged 47.0 hours. Mean income from platform work as a percentage of the national median was 20.6% (SD 22.2). The mean WHO-5 Well-Being Index score was 58.7 (SD 20.3), which is notably lower than the European general population average (69.4), indicating poorer mental health outcomes among cohort members. Future plansThe GIG-OSH cohort represents the first large-scale, longitudinal study examining occupational safety and health among digital platform workers across multiple European countries. Future waves will prioritize developing precise tools to measure hourly earnings and unpaid waiting time. Future research should aim to include underrepresented subgroups, such as medical and domestic care workers, and explore potential linkage with administrative records to evaluate long-term health trajectories and the impact of new EU labour regulations. Strengths and limitations of this studyO_LIThis is the first large-scale longitudinal cohort to examine occupational safety and health among platform workers across multiple European countries, addressing an important evidence gap. C_LIO_LIThe inclusion of both web-based and on-location workers enables comparative analyses across diverse task types, employment conditions, and national contexts. C_LIO_LIRecruitment strategies tailored to national contexts enhanced feasibility but limited the representativeness of samples and precluded national-level weighting or benchmarking. C_LIO_LIHigh attrition between waves and the absence of harmonized classifications (e.g., education levels) across countries may constrain the generalizability and longitudinal consistency of findings. C_LIO_LIDespite relying on self-reported data, the study used stakeholder-informed instruments and captured a wide range of occupational hazards--such as psychosocial and algorithmic risks--not typically addressed in conventional labour surveys. C_LI

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The Effect of Occupational Integration on Musculoskeletal Injury in Female Marines in the Fleet: An Epidemiological Cohort Study

Fraser, J. J.; Zouris, J. M.; Hoch, J. M.; Sessoms, P. H.; MacGregor, A. J.; Hoch, M. C.

2026-02-23 occupational and environmental health 10.64898/2026.02.19.26346637 medRxiv
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IntroductionMusculoskeletal injuries (MSKIs) are ubiquitous in the U.S. military, especially among high-performing service members such as Marines. Given that female service members only started to be assigned to ground combat roles since December 2015, evaluation of sex on MSKI risk in ground combat occupations has not been possible until there was an ample population to study. The purpose of this population-level epidemiological study was to assess (1) if female sex was a salient risk factor for MSKI in Marines serving in different military occupations, including combat arms, and (2) the effects of integration period on MSKI risk among female Marines. Materials and MethodsA population-based epidemiological retrospective cohort study of all U.S. Marines was performed assessing female sex, occupation, and integration period on the prevalence of MSKI from 2011 through 2020. The Military Health System Data Repository was utilized to identify initial healthcare encounters for diagnosed ankle-foot, knee, lumbopelvic-hip, thoracocostal, cervicothoracic, shoulder, elbow, or wrist-hand complex injuries. Prevalence was calculated for female and male Marines in each occupational category (combat, combat support, aviators, aviation support, services) during the pre-integration (2011-2015) and post-integration (2016-2020) periods. ResultsDuring the pre-integration period, 520/1,000 female Marines (n=13,985) and 299/1,000 male Marines (n=142,158) incurred MSKIs. In the post-integration period, the prevalence increased to 565/1,000 female Marines (n=17,608) and 348/1,000 male Marines (n=161,429). In the multivariable evaluation of sex, occupation, integration period, and the interaction of sex and occupation on combined MSKIs, only female sex was a significant factor for injury (prevalence ratio [PR]=1.99), with service in ground combat and aviation occupations identified as protective factors when compared with services occupations (PR=0.69). When these same factors were evaluated for specific MSKI outcomes, female sex remained a robust factor in all lower quarter (PR=1.75-2.63) and upper quarter (PR=1.38-2.36) injuries except for shoulder injuries. Service in ground combat and aviation occupations was protective for all lower quarter injuries (PR=0.46-0.71). In the upper quarter, ground combat was protective for all injuries except for elbow injuries (PR=0.67-0.77). Serving as an aviator was a risk factor for cervicothoracic (PR=1.57) and thoracocostal (PR=1.22) injuries and a protective factor for shoulder (PR = 0.73) and wrist-hand (PR = 0.46) injuries. Adjusted risk for lumbopelvic-hip (PR=1.13), ankle-foot (PR=1.53), cervicothoracic (PR=1.19), thoracocostal (PR=1.14), and elbow (PR=1.48) injuries significantly increased during the post-integration period. There was a significant sex-by-period interaction for shoulder injuries alone, with female sex in the post-integration epoch found to be salient (PR=1.26). ConclusionsFemale sex was a salient factor for MSKI, with service in ground combat and aviation occupations identified as protective factors when compared with services occupations. In the evaluation of specific MSKIs, female sex remained a robust and significant factor in all lower quarter injuries and upper quarter injuries except for shoulder injuries. There was only a significant sex-by-period interaction for shoulder conditions, with an increased risk of these injuries in female Marines in the post-integration period.

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Sickness presenteeism due to respiratory infection in the English workforce: prevalence estimates and demographic factors from the Winter COVID-19 Infection Study (WCIS)

Burdon, M. G.; Denson, S.; Tang, M.; Mellor, J.; Ward, T.

2026-02-16 public and global health 10.64898/2026.02.13.26346245 medRxiv
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BackgroundWorking while sick (presenteeism) with an infectious disease contributes to the spread of infections and is detrimental to productivity. Respiratory illnesses are a common cause of sickness in the working population and understanding the prevalence of presenteeism linked to respiratory illness is therefore important. MethodsWinter Covid Infection Study (WCIS) panel members in work aged 18-64 were surveyed in February - March 2024 and asked about presenteeism in the previous 28 days. Multilevel regression and poststratification was used to estimate the prevalence and length of presenteeism and its effect on productivity in the English workforce, as approximated using the WCIS survey sample calibrated to census proportions. Differences by demographic groups and work sector were also analysed. ResultsAround one in six working adults in England worked while sick with a respiratory infection during the study period, and one in ten attended a non-home workplace. Overall, around one day per adult was spent working while sick with a respiratory infection, approximately half of which was non-home working. Respondents felt they were able to work at around three-quarters of their usual capacity while sick. Presenteeism was more common among respondents who were younger, White, worked in a hybrid pattern, lived in larger households, had Long COVID-19, or worked in teaching and education. ConclusionWorking while sick with a respiratory infection is relatively common, including among those who primarily work away from the home. Key messagesAround one in six working-age adults in employment worked while sick with a respiratory infection during the study period (Feb-Mar 2024). - The likelihood of working while sick with a respiratory infection varied by demographic group and work sector. - On average, survey respondents said they could work at around three quarters their normal effectiveness while sick with a respiratory infection.

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Years Lived without Chronic Diseases after Statutory Retirement - A Register Linkage Follow-up Study in Finland 2000-2021

Pietilainen, O.; Salonsalmi, A.; Rahkonen, O.; Lahelma, E.; Lallukka, T.

2026-04-13 public and global health 10.64898/2026.04.12.26348889 medRxiv
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Objectives: Longer lifespans lead to longer time on retirement, despite the efforts to raise the retirement age. Therefore, it is important to study how the retirement years can be spent without diseases. This study examined socioeconomic and sociodemographic differences in healthy years spent on retirement. Methods: We followed a cohort of retired Finnish municipal employees (N=4231, average follow-up 15.4 years) on national administrative registers for major chronic diseases: cancer, coronary heart disease, cerebrovascular disease, diabetes, asthma or chronic obstructive pulmonary disease, dementia, mental disorders, and alcohol-related disorders. Median healthy years on retirement and age at first occurrence of illness (ICD-10 and ATC-based) in each combination of sex, occupational class, and age of retirement were predicted using Royston-Parmar models. Prevalence rates for each diagnostic group were calculated. Results: Most healthy years on retirement were spent by women having worked in semi-professional jobs who retired at age 60-62 (median predicted healthy years 11.6, 95% CI 10.4-12.7). The least healthy years on retirement were spent by men having worked in routine non-manual jobs who retired after age 62 (median predicted healthy years 6.5, 95% CI 4.4-9.5). Diabetes was slightly more common among lower occupational class women, and dementia among manual working women having retired at age 60-62. Discussion: Healthy years on retirement are not enjoyed equally by women and men and those who retire early or later. Policies aiming to increase the retirement age should consider the effects of these gaps on retirees and the equitability of those effects.

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Heat Exposure, Occupational Injury Risk, and Economic Costs in New York State

Laskaris, Z.; Baron, S.; Markowitz, S. B.

2026-04-22 occupational and environmental health 10.64898/2026.04.20.26351297 medRxiv
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ObjectivesRising temperatures are a major climate-related hazard for U.S. workers, increasing heat-related illness and a broad range of occupational injuries through indirect pathways often overlooked in economic evaluations. We examined the association between temperature and occupational injury and illness and quantified heat-attributable injuries (including illnesses) and costs in New York State. MethodsWe conducted a time-stratified case-crossover study of 591,257 workers compensation (WC) claims during the warm season (2016-2024). Daily maximum temperature was linked to injury date and county and modeled using natural cubic splines, with effect modification by industry and worker characteristics. ResultsInjury risk increased with temperature, becoming statistically significant at approximately 78{degrees}F. Relative to 65{degrees}F, injury odds increased to 1.06 (95% CI: 1.01-1.10) at 80{degrees}F, 1.12 (1.07-1.18) at 90{degrees}F, and 1.17 (1.11-1.23) at 95{degrees}F. Overall, 5.0% of claims (2,322 annually) were attributable to heat. At temperatures [≥]80{degrees}F, an estimated 1,729 excess injuries occurred annually, generating approximately $46 million in WC costs. An estimated $3.2 million to $36.1 million in medical expenditures were associated with incomplete claims, likely borne outside the WC system. ConclusionsThese findings demonstrate substantial economic costs not fully captured within WC and support workplace heat protections as a cost-containment strategy that can reduce health care spending and strengthen workforce resilience.

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Employment status, occupational profile, and common mental disorders among workers in urban informal settlements in Brazil

Cavalcanti Prestes, J. F.; Nunes, T. S.; Souza, F. N.; de Carvalho Santiago, D. C.; Lopez, Y. A.; Goncalves Palma, F. A.; Santana, J. O.; dos Santos, P. E. F.; de Olieveira, D.; Awoniyi, A. M.; Stauber, C. E.; Costa, F.; Cremonese, C.

2026-04-07 epidemiology 10.64898/2026.04.01.26350007 medRxiv
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Urban informal settlements (referred to as favelas in Brazil), reflect longstanding socioeconomic and racial inequalities and are home to a workforce frequently exposed to precarious employment conditions. This study describes the socio-occupational characteristic and estimates the prevalence of common mental disorders (CMDs) among workers residing in five urban informal communities in Salvador, Bahia, Brazil. A cross-sectional epidemiological study (n=587) was conducted with formal and informal workers aged 18-70 years. The outcome was measured using the Self-Reporting Questionnaire-SRQ-20, and associations were evaluated using Poisson Regression, with analysis stratified by employment type. Data analysis was performed using R 3.6.0+ software. The overall prevalence of CMD was 14.0%, increasing to 22.7% among informal workers. In the adjusted analysis of the overall sample, informal employment and persistent fear of job loss were associated with a higher prevalence of mental health problems, whereas the 40-49 age groups showed a lower prevalence of CMD compared with younger workers. In stratified analyses, female sex and job insecurity were associated with CMD among formal workers, while lower monthly income (<$181) was an important among informal workers. This pioneering study highlights the role of precarious employment conditions in the social determination of mental health distress among residents of urban informal communities.

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The wellbeing paradox: High resilience and psychological distress in the transition out of UK policing

Vaportzis, E.; Edwards, W.

2026-03-16 occupational and environmental health 10.64898/2026.03.14.26348403 medRxiv
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This study investigated the wellbeing of UK police officers transitioning out of service, examining retirees, early leavers, and those within 12 months of retirement (N = 370). Using the Job Demands-Resources model, the research identifies a wellbeing paradox: leavers demonstrate high resilience and subjective wellbeing alongside significantly elevated psychological distress compared to general population norms. Findings reveal that recently retired ([&le;]5 years) and soon-to-retire groups are particularly vulnerable, reporting lower quality of life and higher distress than long-term retirees. Perceived organisational support and resilience emerged as critical buffers against the psychological burden of a policing career. However, participants identified significant unmet needs for career, financial, and mental health guidance during the transition. The study highlights that the anticipatory retirement period is an acute window of vulnerability, suggesting that proactive, targeted organisational interventions are essential to mitigate the lasting psychological burden of policing and ensure successful civilian transitions.

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Mortality burden of outdoor occupational heat exposure in the United States

Shkembi, A.; Schinasi, L. H.; Payne-Sturges, D.; Neitzel, R. L.

2026-01-30 occupational and environmental health 10.64898/2026.01.29.26345131 medRxiv
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BackgroundOutdoor workers are particularly vulnerable to the adverse impacts of heat, but many studies focus on heat exposure in residential settings only. This leads to a limited understanding of the full mortality burden due to occupational heat exposures. Here, we aimed to improve estimates of the total, short-term mortality burden attributable to outdoor occupational heat exposure in the United States (US). MethodsWe developed a panel data set for 3,108 US counties during 2010-2019 by linking all-cause mortality among the working age population, derived from CDC WONDER, with the prevalence of workers exposed to outdoor occupational heat, which integrates data on wet bulb globe temperature, workplace activities, and employment counts. We developed a quasi-Poisson regression model adjusted for ambient temperature, total precipitation, and county and state-year fixed effects to estimate short-term excess deaths attributable to outdoor occupational heat exposure. FindingsNationwide, approximately 3.8% (95% CI: 2.5-5.8%) of all workers were annually exposed to dangerous wet-bulb globe temperatures. This outdoor occupational heat exposure resulted in approximately 9,800 (3,100-17,000) annual excess deaths in the working age population. An estimated 62% of excess deaths occurred in the most socially vulnerable counties despite accounting for 25% of workers. InterpretationThe mortality burden of occupational heat exposure is likely far larger than 39 officially reported annual deaths that the Bureau of Labor Statistics reports for this time period. The workplace should be an explicit focus of heat policies, advocacy, and adaptation measures. FundingUS Centers for Disease Control and Prevention/National Institute for Occupational Safety and Health.

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Occupational and Environmental Challenges and Effects of COVID-19 Testing Implementation Experienced by HIV Viral Load Laboratory Staff within a Public Health Sector Laboratory in South Africa

Sarang, S.; Matingo-Mutava, E.; Cassim, N.

2026-02-22 occupational and environmental health 10.64898/2026.02.16.26346134 medRxiv
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BackgroundThe COVID-19 pandemic required South African public sector HIV viral load (VL) laboratories to scale up Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) testing while maintaining essential HIV services. This placed additional pressure on diagnostic services. This dual mandate introduced significant occupational and environmental challenges (OEC) for staff that remain underexplored. ObjectiveThis study aimed to investigate the OEC and effects that staff experienced during the implementation of COVID-19 testing at public sector VL laboratories in South Africa. MethodsA quantitative, cross-sectional study utilised a census approach among technical and support staff. Data were collected via a structured REDCap questionnaire using 5-point Likert scales. Pre- and post-implementation challenges were assessed across four domains: workload, environmental conditions (space, ventilation, waste), communication, and PPE availability. Statistical analyses included the Wilcoxon Signed-Rank and Spearmans correlation tests. ResultsPerceived occupational challenges increased significantly across all domains post-implementation. Staff workload saw the highest rise (mean score 3.02 to 3.53). Adverse health effects were pervasive; 80.2% of staff reported burnout/fatigue, and 76.5% reported increased anxiety/stress. A strong positive correlation was observed between post-COVID-19 challenges and adverse mental and physical health outcomes (rho = 0.449, p < 0.001). Furthermore, 35.8% of staff considered resigning due to increased job demands. ConclusionIntegrating COVID-19 testing exacerbated systemic weaknesses, causing measurable psychological injury and threatening workforce retention. Findings suggest that the diagnostic workforce requires formal crisis surge staffing models and institutionalised mental health support to safeguard personnel and maintain essential services during future health emergencies.

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Vaccine uptake patterns for COVID-19 and cholera among healthcare workers: a cross-sectional study in Yaounde-Cameroon

Nouko, A.; Cheuyem Lekeumo, F. Z.; Nguefack, F.; Tchamani, R.; Takougang, I.

2026-03-13 occupational and environmental health 10.64898/2026.03.12.26348275 medRxiv
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ObjectiveHealthcare workers (HCWs) are at increased risk of COVID-19 infection and play a critical role in influencing public vaccine acceptance. This study aimed to assess vaccination coverage and identify the determinants of vaccine uptake among healthcare workers in Cameroon, in order to inform targeted strategies to strengthen immunization programs and improve epidemic preparedness. ResultsAmong 406 participants (75.6% female, 65.5% aged 30-44 years, 61.3% nurses), 42.4% were fully vaccinated against COVID-19, while only 4.7% had completed the cholera vaccine series. Coverage varied across districts, with Biyem-Assi (53.0%) and Odza (46.0%) recording the highest COVID-19 uptake, and Nkolndongo (11.5%) leading for cholera vaccination. Independent predictors of COVID-19 uptake included being a nurse (aOR = 3.96; 95% CI: 2.07-7.81; p = 0.001) and laboratory technician professions (aOR = 8.00; 95% CI: 1.38-69.8; p =0.032). For cholera vaccination, working in internal medicine wards (aOR=11.2; 95% CI: 1.04-120; p = 0.046) and being a nurse (aOR = 1.54; p = 0.001) emerged as significant predictors. Although 62.8% of HCWs perceived their work environment as high-risk, knowledge of recommended vaccines was limited, with only 18.7% aware of cholera vaccination recommendations. Strengthening vaccine education, improving accessibility, and reducing financial barriers could enhance vaccine acceptance among HCWs. These findings provide important insights for designing targeted immunization strategies in Cameroon and similar contexts.

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Alpha-gal Syndrome Symptom Profiles and Diagnostic Experiences Among Farmer and Ranchers

Welch, A. M.; Beseler, C. L.; Cross, S. T.

2026-04-16 occupational and environmental health 10.64898/2026.04.14.26349898 medRxiv
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Purpose: Alpha-gal syndrome (AGS) is an emerging health issue. This syndrome, caused by the bites of ticks, induces allergic reactions to the sugar molecule galactose-alpha-1,3-galactose after exposure to non-primate mammalian meat and other byproducts. Agricultural workers spend significant time outdoors placing them at an increased risk for tick bites and tick-borne diseases, like AGS. This study aimed to characterize farmers and ranchers' prior knowledge, symptomology, and diagnostic experiences with AGS. Methods: We conducted a cross-sectional survey of more than 200 farmers and ranchers with a self-reported AGS diagnosis. The survey captured farmers and ranchers' experiences related to prior knowledge and experience with tick bites and AGS, reported symptoms, and obtaining a diagnosis. Findings: A total of 201 respondents across 26 states participated in the survey, with the majority from Missouri and Oklahoma. We identified four distinct symptom clusters, with the most reported symptoms being abdominal cramping, diarrhea, itchy skin, and nausea. Women more often reported gastrointestinal discomfort, and men were more likely to be in the mild symptom category. On average, participants reported 2.98 medical provider visits before receiving a diagnosis, most being diagnosed by general practitioners and allergists. Conclusions: No previous studies have focused on the symptom and diagnostic experiences of farmers and ranchers with AGS. Capturing such data is essential as these workers may experience unique occupational challenges following AGS diagnosis. The diagnostic experience data support a continuing need to educate and empower AGS patients and providers, especially agricultural workers and providers serving rural communities.

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The lingering legacy: Resilience mediates the long-term impact of organisational support on police retirement adjustment

Vaportzis, E.; Edwards, W.

2026-04-11 public and global health 10.64898/2026.04.08.26349526 medRxiv
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This study investigated retirement adjustment in retired police officers in the UK (N = 289), examining how time since leaving the service moderates the relationship between perceived organisational support and retirement adjustment while accounting for resilience. Results indicated a developmental trend: organisational support remains stable initially but becomes increasingly influential in later life. Using Johnson-Neyman analysis, a threshold of 32.07 years was identified, after which the association reaches statistical significance. These findings suggest an organisational legacy effect; for the older generation, the retrospective perception of being valued by the service acts as a durable psychological resource. This study offers a novel conceptualisation of long-term organisational influence by identifying a temporally delayed legacy effect that extends beyond existing models of retirement adjustment. The study advocate for lifelong wellbeing strategies that extend, recognising that the organisational relationship continues to shape adjustment outcomes decades after the conclusion of active duty.

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Work-related stress and consumption of psychoactive substances and medications among early childhood professionals in Orleans Metropole, CCTVL, and Fleury-les-Aubrais (TraPsyCOL): Study protocol for a cross-sectional study

KHAZAAL, W.; ONNEE, S.; NAECK, R.; MORISSET-LOPEZ, S.; BARIL, P.; VERNAY, O.; SERREAU, R.

2026-02-27 epidemiology 10.64898/2026.02.25.26347115 medRxiv
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Work-related stress is a major public health issue affecting workers across various sectors. Individuals experiencing work-related stress are more likely to consume psychoactive substances, primarily alcohol, tobacco, and cannabis, as well as psychoactive medications, which may be used as coping mechanisms. Work-related stress is also associated with adverse outcomes such as burnout, depression, anxiety, and sleep disorders. In France, early childhood professionals, including "ATSEMs", "animateurs", and "agents dentretien", play a crucial role in the education, care, and well-being of children but are exposed to high levels of occupational stress due to the emotionally demanding nature of their work and the associated physical strain, making them vulnerable to substance use, burnout, depression, anxiety, and sleep disorders. This cross-sectional epidemiological study, conducted at a single time point, will be carried out among early childhood professionals working in schools for children in Orleans Metropole, Communaute de Communes des Terres du Val de Loire (CCTVL), and Fleury-les-Aubrais. Ethical approval for this study was obtained from the Ethics Committee of the Centre Hospitalier Universitaire dOrleans (assigned reference number is CERO 2511-02). The study aims to provide a better understanding of the relationship between work-related stress and the use of psychoactive substances and medications among early childhood professionals, as well as the association between work-related stress and burnout, depression, anxiety, and sleep disorders. Data will be collected anonymously using self-administered online questionnaires, accessed via a QR code printed on flyers distributed to participants. The same QR code will also provide access to an information sheet explaining that the study complies with ethical guidelines and that proceeding implies non-objection to participation. Based on calculations performed using BiostaTGV, a sample size of 265 participants is required. Statistical analysis will be conducted using SPSS software. Studying these associations is essential for informing the development of targeted interventions and prevention.

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The Beat Goes On: A Mixed-Methods Analysis in Developing Effective Police Leaver Transitions

Vaportzis, E.; Edwards, W.

2026-03-31 occupational and environmental health 10.64898/2026.03.26.26348236 medRxiv
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The end-of-career stage of the police lifecycle represents a profound shift in identity and psychological stability, yet it remains historically neglected in research. This mixed-methods study investigated perspectives of UK police leavers and those approaching retirement (N = 325) regarding desired improvements to organisational support. Content analysis identified four themes: Holistic support and long-term welfare, Institutional culture and professional worth, Navigating the structural transition, and Individual and systemic perspectives. Findings suggest that the psychological contract between the officer and the organisation is often breached at the exit point, shifting from a relational bond to a transactional disposal. Middle-ranking officers and early leavers report the highest levels of institutional abandonment. To address these gaps, this paper makes recommendations for developing effective transitions. By implementing post-service welfare, and adopting structured resettlement models, police organisations can fulfil their duty of care and mend the psychological contract for those who have served.

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Area-Level Economic Opportunity Modifies the Income-Health Gradient in the United States

Mishra, A.; O'Brien, R.; Venkataramani, A. S.

2026-03-30 health economics 10.64898/2026.03.27.26349545 medRxiv
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Introduction: Economic opportunity is a core pillar of the American Dream but is not distributed equally across communities. Substantial evidence has identified economic opportunity as an independent social determinant of health, but relatively little is known about opportunity's relationship with other socioeconomic characteristics such as income. Here we address this gap in the literature to examine how area-level economic opportunity modifies the income-health gradient. Methods: We used multivariable ordinary least squares models to estimate the association between self-reported health and economic opportunity across household income levels for working age adults (ages 25-64). Our measures of income and health come from the 2010-2019 Current Population Survey Annual Social and Economic Supplements. Our measure of economic opportunity was drawn from Opportunity Insights and represents the county-averaged national income percentile rank attained in adulthood for individuals born to parents at the 25th percentile of the income distribution. We adjusted for a wide range of individual- and county-level demographic and socioeconomic characteristics. Results: We find that county-level economic opportunity modified the gradient in self-reported health and household income among working-age adults. Effects were particularly pronounced in the lowest income deciles -- an interdecile increase in economic opportunity was associated with closing almost 33% of the gap in health between the lowest and highest income deciles. The results were robust to sensitivity analyses. Conclusion: We show that local area economic opportunity flattens the relationship between household income and health, with lower-income individuals benefitting the most from living in high opportunity areas.

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Playing position and long-term mortality among elite male football players, 1930-1990

Witteveen, D.; Humphreys, D. K.

2026-02-17 epidemiology 10.64898/2026.02.16.26346414 medRxiv
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BackgroundConcern about long-term health effects of repetitive head impacts in football has increased, but it remains unclear whether position-specific exposure patterns were associated with differential long-term all-cause mortality among elite players across the 20th century. MethodsWe conducted two retrospective cohort studies of elite male professional football players. The World Cup cohort included all players on the team rosters from FIFA World Cup tournaments (1930-1990), and the UEFA European Cup cohort included all players who appeared in annual quarterfinal, semifinal, or final matches (1956-1991). Vital status was ascertained through archival linkage. Playing position was harmonized into six categories. Age was the time scale. Cox proportional hazards models were stratified by birth cohort and adjusted for origin region; interaction models were used to estimate region-specific marginal hazard ratios. FindingsThe World Cup cohort included 4,223 players (2,330 deaths), and the European Cup cohort included 2,710 players (1,126 deaths). In the World Cup cohort, goalkeepers had lower mortality than midfielders (hazard ratio [HR] 0.73, 95% CI 0.63-0.84), whereas center-forwards had higher mortality (HR 1.27, 95% CI 1.08-1.50); mortality among center-backs was elevated but not statistically significant (HR 1.13, 95% CI 0.98-1.31). In the European Cup cohort, center-backs (HR 1.28, 95% CI 1.07-1.55) and other defenders (HR 1.20, 95% CI 1.02-1.42) had higher mortality than midfielders. Region-stratified marginal estimates indicated that elevated risks for central playing roles were greatest in Northwestern Europe and Central/Eastern Europe. InterpretationAmong footballers active during the 20th century, long-term all-cause mortality differed by playing position and varied by region, with higher risks concentrated in central attacking and defensive roles. These patterns were most pronounced in regions where aerial contests historically predominated, suggesting that long-term health risks associated with professional football participation vary by role-specific exposure profiles.

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Epidemiological Assessment of Accidents and Functional Limitations among Nursing Home Residents in Shiraz, Iran (2024)

Fallah, H.; Sheibani, M.; Rezaeipandari, H.

2026-02-02 epidemiology 10.64898/2026.01.30.26345186 medRxiv
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BackgroundWith the rapid ageing of Irans population, accidents among institutionalised older adults represent a major public health concern. This study aimed to determine the prevalence, characteristics, and risk factors of accidents among elderly residents of nursing homes in Shiraz, Iran, during 2024, with particular emphasis on functional limitations. MethodsA cross-sectional census-based study was conducted in all seven nursing homes in Shiraz, involving 550 residents aged [&ge;]60 years. Data were collected through structured interviews, review of medical records, caregiver reports, and an Accident Form. Accidents occurring during the previous year were analyzed using descriptive statistics, and associations between accident occurrence and participant characteristics were examined using chi-square tests. ResultsOverall, 72.0% of residents experienced at least one accident during the study period. Slipping was the leading cause, and bathrooms and toilets were the most frequent locations. Contusion or bruising was the most common outcome. Mobility limitation was the only factor significantly associated with accident occurrence (p < 0.001), whereas age, gender, marital status, and educational level showed no significant associations. ConclusionsAccidents were common among nursing home residents in Shiraz and were strongly associated with mobility limitation. These findings highlight the importance of addressing functional impairments alongside environmental hazards through targeted ergonomic modifications and mobility-support interventions.

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Internal and External Protective Factors Associated with the Secondary Traumatic Stress Component of Compassion Fatigue in Feral Cat Caregivers

Costa-Santos, C.; Vidal, R.; Lisboa, S.; Vieira-de-Castro, P.; Monteiro, A.; Duarte, I.

2026-03-06 occupational and environmental health 10.64898/2026.03.05.26347725 medRxiv
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Compassion fatigue is a well-documented hazard among healthcare and veterinary professionals, yet the psychological toll on informal caregivers of feral cat colonies, likely numbering several tens of thousands in Portugal, remains largely unexplored. This cross-sectional study examines internal and external factors associated with the secondary traumatic stress component of compassion fatigue among 172 informal caregivers in Portugal. Secondary traumatic stress refers to work-related secondary exposure to individuals who have experienced extremely stressful or traumatic events. Structured telephone interviews assessed sociodemographics, colony management, compassion satisfaction, resilience, spiritual well-being, and perceived social support. Univariate and multivariable linear regression identified predictors of secondary traumatic stress. Results indicate that 47% of participants experienced moderate secondary traumatic stress, and 10% reported high levels. Multivariable analysis revealed that caring for large colonies (more than 25 cats) and being unemployed were significantly associated with higher fatigue. Conversely, older age, higher perceived family support, and the resilience dimension of serenity served as protective factors. Interestingly, finding meaning in life was positively correlated with fatigue, suggesting that caregivers who perceive their role as central to their life purpose may become more emotionally invested, increasing vulnerability to distress when unable to help animals. Official colony registration and formal institutional support did not significantly alleviate fatigue. These findings highlight that institutional support alone is insufficient to mitigate fatigue among informal caregivers, who experience significant distress driven by both practical burdens and profound emotional involvement. The most frequently reported concern among caregivers was the inability to cover the costs of feeding and veterinary care for the cats. Interventions must address both external needs (e.g., support to cover veterinary and feeding expenses for the cats) and internal coping mechanisms. Implementing psychosocial support alongside trap-neuter-return programs may also improve caregiver well-being and foster sustainable urban feral cat management. This underscores a One Health perspective, demonstrating that animal health is closely interconnected with human well-being and environmental health.

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An Assessment of Correctional Officer's Health Beliefs in Relationship to COVID-19 Vaccine Uptake and Hesitancy.

Hedden-Clayton, B.; Roddy, A. L.; Roddy, J. K.; Ngassa, Y.; Pickard, B.; Tam, R. A.; Wurcel, A. G.

2026-03-26 public and global health 10.64898/2026.03.24.26349101 medRxiv
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IntroductionDuring the COVID-19 pandemic, incarcerated populations faced heightened risk of exposure due to healthcare barriers, restrictive environments, and pre-existing health conditions. Consequently, Correctional Officers (COs) faced increased risk of COVID-19 exposure. Given the health benefits of COVID-19 vaccination and the rise in vaccine hesitancy, this study examined the relationship between COs health beliefs and COVID-19 vaccine uptake. MethodsA health beliefs survey was administered to Massachusetts-based COs (n=118). Chi-squared Automatic Interaction Detection modeling and logistic regression was utilized to analyze the survey data. ResultsCOs with higher trust in vaccines and a prior positive COVID-19 test were most likely to get vaccinated voluntarily. Those with low trust in vaccines and no previous positive COVID-19 test were least likely to receive the vaccine. ConclusionDespite the severe impact of COVID-19 in correctional settings, and the evidence of vaccine efficacy against hospitalization and death, vaccine uptake among COs remains low.